Table 2.
CMV peptides tested for T cell responses in 6 mother-infant pairs.
| HLA restriction | CMV protein | Amino acid sequence | Mother | Infant | Novel (adults) | Novel (infants) |
|---|---|---|---|---|---|---|
| A*01 | UL83 | YSEHPTFTSQY | X | |||
| A*02 | UL83 | NLVPMVATV | ||||
| MLNIPSINV | X | |||||
| RLLQTGIHV | X | |||||
| RIFAELEGV | ||||||
| UL123 | VLEETSVML | |||||
| TMYGGISLL | ||||||
| A*03 | UL123 | RIKEHMLKK | ||||
| KLGGALQAK | X | |||||
| A*11 | UL83 | ATVQGQNLK | X | |||
| GPISGHVLK | X | |||||
| UL123 | STHPMVTRSK | X | ||||
| A*26 | UL83 | DIYRIFAEL | ||||
| A*30 | UL83 | RQYDPVAAL | ||||
| B*07 | UL83 | TPRVTGGGAM | ||||
| RPHERNGFTVL | X | |||||
| B*08 | UL123 | QIKVRVDMV | ||||
| B*13 | UL83 | TRATKMQVI | ||||
| UL123 | YILGADPLRV | |||||
| B*18 | UL83 | NEIHNPAVF | X | X | ||
| DEELVTTER | X | X | ||||
| UL123 | DELRRKMMY | X | ||||
| DEEEAIVAY | X | |||||
| TEEKFTGAF | X | |||||
| B*35 | UL83 | IPSINVHHY | X | |||
| CPSQEPMSIYVY | ||||||
| B*37 | UL123 | LDEERDKVL | ||||
| B*40 | UL83 | CEDVPSGKL |
Shaded boxes, CMV-specific response detected in at least one mother or infant in the cohort. X, novel peptides not previously reported as CD8 T cell epitopes in adults or infants.