Table 4.
Demographic, behavioral, and clinical characteristics in the sample of men with HIV by cognitive profile.
| Profile 1 | Profile 2 | Profile 3 | ||
|---|---|---|---|---|
|
Unimpaired (n = 753) n (%) |
Relative strength in attention and processing speed (n = 286) n (%) |
Global weaknesses (n = 426) n (%) |
P-value | |
| Age, M (SD) | 40.6 (9.1) | 41.9 (9.8) | 44.3(10.6) | <0.001 |
| Years of education, M (SD) | 13.4 (2.52) | 13.7 (2.6) | 13.6 (2.9) | 0.245 |
| WRAT-4, M (SD) | 99.7 (12.8) | 104.1 (11.8) | 96.8 (14.5) | <0.001 |
| Race | 0.01 | |||
| White | 432 (57) | 188 (66) | 270 (63) | |
| Black | 146 (19) | 48 (17) | 65 (15) | |
| Hispanic | 139 (19) | 31 (11) | 76 (18) | |
| Other | 36 (5) | 19 (6) | 15 (4) | |
| IADL complaints | 2.2 (2.7) | 1.4 (1.9) | 3.4 (3.3) | <0.001 |
| BDI | 13.1 (10.4) | 10.5 (9.) | 16.2 (10.7) | <0.001 |
| CIDI diagnoses | ||||
| MDD | ||||
| Current | 105 (19) | 21 (10) | 77 (24) | <0.001 |
| Lifetime | 259 (47) | 92 (45) | 159 (49) | 0.66 |
| Alcohol (current or lifetime*) | 40 (7) | 3 (1) | 23 (7) | 0.009 |
| Cannabis (current or lifetime*) | 36 (7) | 8 (4) | 16 (5) | 0.31 |
| Substance use (current or lifetime*) | 321 (74) | 121 (73) | 183 (72) | 0.90 |
| Anticholinergic medication | 195 (26) | 48 (17) | 124 (29) | <0.001 |
| Hypertension | 140 (19) | 51 (19) | 107 (26.) | 0.01 |
| Hyperlipidemia | 96 (13) | 40 (15) | 57 (14) | 0.82 |
| Diabetes | 40 (5) | 8 (3) | 22 (5) | 0.22 |
| HCV | 125 (17) | 46 (17) | 88 (21) | 0.14 |
| Log plasma viral load, M (SD) | 3.2 (1.3) | 2.9 (1.3) | 3.2 (1.5) | 0.01 |
| CD4 count, M (SD) | ||||
| Current | 432.4 (301.1) | 479.0 (272.8) | 381.4 (295.0) | <0.001 |
| Nadir | 238.6 (232.8) | 268.2 (209.8) | 188.8 (196.1) | <0.001 |
| Duration of HIV disease, M (SD) | 8.9 (7.8) | 8.5 (7.4) | 10.4 (8.6) | 0.01 |
| AIDS diagnosis | 440 (56) | 113 (47) | 281 (66) | <0.001 |
| On ART | 426 (58) | 166 (59) | 265 (64) | 0.10 |
ART, antiretroviral therapy; WRAT-4, Wide Range Achievement Test; IADL, Instrumental Activities of Daily Living; BDI, Beck depression inventory; CIDI, Composite International Diagnostic Interview; HCV, Hepatitis C;
*
Current or Lifetime Use disorder (abuse or dependence).