Table 5.
Demographic, behavioral, and clinical characteristics in the sample of women with HIV by cognitive profile.
| Profile 1 | Profile 2 | Profile 3 | ||
|---|---|---|---|---|
| Weakness in motor function | Relative weaknesses in learning and memory | Global weaknesses with spared verbal recognition | P-value | |
| (n = 64) | (n = 70) | (n = 67) | ||
| n (%) | n (%) | n (%) | ||
| Age, M (SD) | 37.4 (8.5) | 42.4 (9.9) | 41.9 (9.8) | 0.005 |
| Years of education, M (SD) | 11.5 (2.5) | 12.6 (2.4) | 11.9 (2.6) | 0.03 |
| WRAT-4, M (SD) | 96.6 (9.8) | 95.5 (13.9) | 88.9 (13.5) | 0.003 |
| Race | 0.007 | |||
| White | 21 (33) | 32 (46) | 28 (42) | |
| Black | 16 (25) | 26 (37) | 13 (19) | |
| Hispanic | 25 (39) | 8 (11) | 20 (30) | |
| Other | 2 (3) | 4 (6) | 6 (9) | |
| IADL dependence | 2.7 (3.0) | 2.2 (2.7) | 3.8 (3.5) | 0.01 |
| BDI-II | 13.7 (9.5) | 10.9 (9.2) | 16.0 (10.5) | 0.01 |
| DSM-IV (CIDI) diagnoses | ||||
| MDD | ||||
| Current | 5 (14) | 2 (5) | 14 (34) | 0.003 |
| Lifetime | 17 (47) | 17 (45) | 28 (68) | 0.06 |
| Alcohol (current or lifetime*) | 3 (8) | 2 (5) | 1 (2) | 0.51 |
| Cannabis (current or lifetime*) | 1 (3) | 2 (5) | 0 (0) | 0.34 |
| Substance use (current or lifetime*) | 22 (81) | 21 (66) | 21 (67) | 0.36 |
| Anticholinergic medication | 16 (25) | 18 (26) | 21 (31) | 0.66 |
| Hypertension | 8 (12) | 16 (23) | 12 (18) | 0.28 |
| Hyperlipidemia | 5 (8) | 9 (13) | 12 (18) | 0.21 |
| Diabetes | 5 (8) | 2 (3) | 58 | 0.4 |
| HCV | 22 (34) | 18 (26) | 18 (27) | 0.53 |
| Log plasma viral load, M (SD) | 3.1 (0.9) | 3.1 (1.2) | 3.2 (1.3) | 0.72 |
| CD4 count, M (SD) | ||||
| Current | 448.4 (282.9) | 516.5 (309.6) | 358.2 (304.7) | 0.01 |
| Nadir | 298.6 (269.1) | 273.1 (232.0) | 181.3 (173.5) | 0.009 |
| Duration of HIV disease, M (SD) | 7.3 (5.4) | 7.41 (6.1) | 6.5 (5.3) | 0.76 |
| AIDS diagnosis | 32 (50) | 36 (51) | 47 (70) | 0.03 |
| On ART | 34 (55) | 36 (52) | 39 (61) | 0.58 |
ART, antiretroviral therapy; WRAT-4, Wide Range Achievement Test; IADL, Instrumental Activities of Daily Living; BDI, Beck depression inventory; CIDI, Composite International Diagnostic Interview; HCV, Hepatitis C;
*
Current or Lifetime Use disorder (abuse or dependence).