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. 2020 Nov 24;10:592757. doi: 10.3389/fonc.2020.592757

Figure 2.

Figure 2

LncRNA SNHG7 was highly expressed in chemoresistant breast cancer cells. (A) The expression of SNHG7 in 5 breast cancer cell lines (MCF-7, T47D, SKBR3, MD-MB231, BT549) and normal human mammary gland epithelial cell line (MCF-10A) determined by qRT-PCR. (B) The viability of MCF-7/ADR and the parental MCF-7 cells, and the IC50 values of adriamycin were determined by MTT assay after exposure to different concentrations of adriamycin for 48 h. (C) The viability of MDA-MB-231/PTX cells and the parental MDA-MB-231 cells,and the IC50 values of paclitaxel were determined by MTT assay after exposure to different concentrations of paclitaxel for 48 h. (D) The lncRNA SNHG7 expression level was increased in chemoresistant cell lines (MCF-7/ADR and MDA-MB-231/PTX) compared with parental cell lines (MCF-7 and MDA-MB-231). *P < 0.05.