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. 2020 Nov 24;10:590931. doi: 10.3389/fonc.2020.590931

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Copyright © 2020 Yang, Xia, Li, Chen, Zhao, Sun, Ma, Wu, Wang, Wang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of propofol infusion on GluR2 and DMT1 in two areas 18 days after glioma model establishment. (A) Western blotting result showed expression of GluR2 in the 2-mm diameter periphery of the gliomas. (B) Expression of GluR2 in the core of the gliomas. (C) Quantification of GluR2 expression and comparison within periphery and core groups. (D) DMT1 expression in the 2-mm diameter periphery of gliomas. (E) DMT1 expression in the core of the gliomas. (F) Quantification of DMT1 expression and comparison within the periphery and core groups. Data are presented as the mean ± SD (n=6/group). ^*P < 0.05 and ^**P < 0.01. Groups: S, sham; G, glioma; P1 and P2, propofol 20, and 40 mg/kg^-1/h^-1, respectively. DMT1, divalent metal transporter 1.