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. 2020 Nov 24;10:590931. doi: 10.3389/fonc.2020.590931

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Copyright © 2020 Yang, Xia, Li, Chen, Zhao, Sun, Ma, Wu, Wang, Wang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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On day 18 after C6 glioma model establishment, CSF was withdrawn from rats, and the total GSH content and GSH/GSSG ratio was determined. (A) Quantification of total GSH content in CSF (n=6/group). (B) The analysis of GSH/GSSG ratio (n=6/group). Data are presented as means ± SD. ^*P < 0.05 and ^**P < 0.01. Groups: S, sham; G, glioma; P1 and P2, propofol 20, and 40 mg/kg^-1/h^-1, respectively. CSF, cerebrospinal fluid; GSH, glutathione; GSSG, glutathione disulfide.