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. 2020 Nov 24;11:556104. doi: 10.3389/fneur.2020.556104

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Copyright © 2020 Nowak, Muppidi, Beydoun, O'Brien, Yountz, Howard and for the REGAIN study group.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.>

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Overall changes to immunosuppressive therapy (IST) at any time during the open-label extension (OLE) in patients using prednisone and related corticosteroids (PRED), azathioprine (AZA), or mycophenolate mofetil (MMF). During the OLE, 94 patients used PRED (90 patients at OLE baseline), 39 patients used AZA (39 patients at OLE baseline), and 34 patients used MMF (30 patients at OLE baseline). ^aIncreases/decreases were calculated from the starting dose and the dose at the last assessment.