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. Author manuscript; available in PMC: 2020 Dec 11.
Published in final edited form as: ACS Chem Neurosci. 2020 May 4;11(10):1471–1481. doi: 10.1021/acschemneuro.0c00114

Figure 4.

Figure 4.

Fluorescence microscopy images of brain sections from 5×FAD mice treated with L1 for 30 days. The brain sections were immunostained with the AF594-HJ3.4 antibody. The fluorescence signals from AF594-HJ3.4 antibody and L1 were monitored at 600–660 nm and 435–485 nm under excitation at 340–380 nm and 540–580 nm, respectively (AF594-HJ3.4 antibody, red; L1, blue; scale bar 100 μm). The in vivo L1 was appreciably colocalized with the amyloid plaques immunostained with AF594-HJ3.4 (Pearson’s correlation coefficient 0.41).