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. 2020 Nov 25;11:577971. doi: 10.3389/fneur.2020.577971

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Copyright © 2020 Achmus, Ruhnau, Grothe, von Sarnowski, Bröker, Dressel, Schulze and Vogelgesang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Myeloid-derived suppressor cells (MDSCs) were measured in stroke patients in comparison to healthy controls. Monocytic MDSCs (Mo-MDSC; CD11b⁺/CD14⁺/HLA-DR^dim/−) (A); granulocytic or polymorphonuclear MDSCs (PMN-MDSCs; CD11b⁺/CD15⁺/CD14⁻) (B); and early MDSCs (e-MDSCs; Lin⁻/HLA-DR⁻/CD33⁺/CD11b⁺) (C) were measured in 27 stroke patients (black dots) in comparison to 16 healthy age-matched controls (white dots) on days 1, 3, and 5 after stroke. Cells were stained extracellularly and analyzed by flow cytometry (LSR II, BD). Median and interquartile range are provided. ***p < 0.001.