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. 2020 Nov 25;11:577971. doi: 10.3389/fneur.2020.577971

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Copyright © 2020 Achmus, Ruhnau, Grothe, von Sarnowski, Bröker, Dressel, Schulze and Vogelgesang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Human leukocyte antigen—DR isotype (HLA-DR) on unstimulated and lipopolysaccharide (LPS)-stimulated monocytes. Peripheral blood mononuclear cells (PBMCs) were left unstimulated (A,B) or treated with 10 ng/ml LPS for 20 h (C,D). HLA-DR was measured as the percentage of expressing cells and the amount of HLA-DR expressed per cell—measured by the geometric mean fluorescence intensity (MFI)—in unstimulated and stimulated conditions. Measurements were performed in 12 stroke patients in comparison to 10 healthy age-matched controls. Median and interquartile range are provided. *p < 0.05.