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. 2020 Nov 24;7:596366. doi: 10.3389/fmolb.2020.596366

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Copyright © 2020 Ha, Choi, Lee, Hong and Lee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Delivery of Aa OMVs into microglial cells. (A) Schematic diagram of intravital imaging process performed in this study. (B) Nanoparticle tracking analysis (NTA) of Aa OMVs used in this study. OMVs from Aa were analyzed using the NanoSight system to visualize the size distribution (X-axis) and particle numbers (Y-axis). (C) Intravital image was captured 24 h after Aa OMV i.v. injection. OMVs were colocalized with GFP-positive microglial cells. Scale bar: 50 μm. Additional Figures can be found in Supplementary Figure S3.