Table 2.

Studies on L-PRF and maxillary sinus augmentation with L-PRF as the SOLE grafting material.

L-PRF as the SOLE grafting material
Patient characteristics	Experimental groups	Methodology and recorded parameters	L-PRF preparation protocol	Surgical intervention	Outcome	References
20 patients (8M/12F) AGE: 59.8 ±11.1 years SA: 23	Study 1: L-PRF (Astra Implants) (7) Study 2: L-PRF (Intra-Lock Implants) (13) Control: No.	2–6 years follow up Retro-alveolar and panoramic X-rays. CT scan or low dose volumetric computed radiography (some cases)	400 g 12 min	Classical lateral sinus-lift using the Caldwell-Luc approach.	Bone gain was 8.5–1.2 mm (mean: 10.4 ±1.2 mm). Crestal bone height was very stable. No Implant Lost The use of L-PRF as sole filling material seems to be a reliable surgical option promoting natural bone regeneration	(61)

AOT, absence of teet; BH, bone height; M, male; F, female; ISQ, Implant stability quotient; NB, new bone; NFB, newly formed bone; NR, not reported; NSC, no statistically comparison; NSSD, no statistically significant difference; RCT, randomized clinical trial; RR, resorption Rate; SA, sinus augmentation; SD, significant difference.