. 2020 Nov 27;7:594788. doi: 10.3389/fcvm.2020.594788

Table 6.

The impact of serum uric acid in atrial fibrillation patients with normal and wide left atrium diameter.

	Age ≤65				Age >65
Tertiles of SUA
Men	T1 (n = 767)	T2 (n = 771)	T3 (n = 764)		T1 (n = 818)	T2 (n = 803)	T3 (n = 809)
AF (n, %)	47 (6.1%)	86 (11.2%)	89 (11.6%)		92 (11.2%)	109 (13.6%)	123 (15.2%)
	OR (95% CI)	OR (95% CI)	OR (95% CI)	P-trend	OR (95% CI)	OR (95% CI)	OR (95% CI)	P-trend
Normal LAEDD	Ref.	2.139 (1.361, 3.361)^†	2.228 (1.397, 3.552)^†	0.001	Ref.	1.116 (0.792, 1.574)	1.094 (0.722, 1.552)	0.639
Large LAEDD	Ref.	1.364 (0.549, 3.389)	2.239 (0.901, 5.567)	0.081	Ref.	1.595 (0.738, 3.450)	2.427 (1.039, 5.667)^*	0.041
Women	T1 (n = 659)	T2 (n = 663)	T3 (n = 644)		T1 (n = 977)	T2 (n = 972)	T3 (n = 971)
AF (n, %)	27 (4.1%)	43 (6.5%)	53 (8.2%)		113 (11.6%)	103 (10.6%)	143 (14.7%)
	OR (95% CI)	OR (95% CI)	OR (95% CI)	P-trend	OR (95% CI)	OR (95% CI)	OR (95% CI)	P-trend
Normal LAEDD	Ref.	1.565 (0.860, 2.848)	1.612 (0.862, 3.014)	0.148	Ref.	0.703 (0.485, 1.019)	0.656 (0.446, 0.966)^*	0.033
Large LAEDD	Ref.	2.074 (0.850, 5.060)	1.534 (0.590, 3.984)	0.381	Ref.	1.739(1.075, 2.812) ^*	1.600 (0.964, 2.658)	0.086

P < 0.05,

^†

P < 0.01.

In men: ≤42 mm considered normal LAD levels; and >42 mm was considered as left atrial enlargement. In women: ≤38 mm was considered normal LAD and >38 mm was considered as left atrial enlargement. Age ≤65 men: SUA-Tertile 1, ≤337.59 μmol/L; SUA-Tertile 2, 337.59-409.00 μmol/L; SUA-Tertile 3,>409.00 μmol/L. Age >65 men: SUA-Tertile 1, ≤323.00 μmol/L; SUA-Tertile 2, 323.00-393.00 μmol/L; SUA-Tertile 3,>393.00 μmol/L. Age ≤65 Women: SUA-Tertile 1, ≤272.00 μmol/L; SUA-Tertile 2, 272.00-337.00 μmol/L; SUA-Tertile 3, >337.00 μmol/L; Age >65 women: SUA-Tertile 1, ≤279.00 μmol/L; SUA-Tertile 2, 279.00-342.00 μmol/L; SUA-Tertile 3,> 342.00 μmol/L. Adjusted for age, SBP, Scr, smoking, dyslipidemia, DM, statin, diuretic, ACEI, ARB, CCB, and β-blocker.