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. 2020 Nov 27;8(11):e22661. doi: 10.2196/22661

Table 5.

Examples of classification results.

Case True label Prediction Sentences
(a) ADEa ADE MTXb + adalimumab administration started. Changed to certolizumab pegol because of MTX’s side effects.
(b) ADE ADE Case: Male, 74 years old. [Previous history]
Rash due to ABPC/SBTc. Anaphylactic shock at CEZd.
(c) ADE Non-ADE MTX was administered to a 59-year-old patient with RAe. In March 201X, she had difficulty breathing and was consulted.
(d) ADE Non-ADE Case: Female, age 79 years.
[Chief complaint]
[Current medical history]
Patient was taking prednisolone 40 mg/d and methotrexate 8 mg/wk. The patient presented with giant cell arteritis and was using insulin for diabetes. Two weeks later, she was hospitalized for malaise and poor appetite.
(e) Non-ADEf ADE Stevens–Johnson syndrome (SJS) is characterized by fever and severe mucosal eruptions of the skin, mucosal transitions involving the eyes, lips, and vulva, and blister and erosion due to erythema and necrotic injury to the epidermis. The majority of cases are considered some of the most severe forms of drug eruption. Others are associated with viral and mycoplasmal infections.
(f) Non-ADE ADE Figure 10 shows a clinical course. According to the reporting system, ~25% (92/372) of all drugs causing TdPg in the past five years were new quinolones (mainly levofloxacin).
(g) Non-ADE Non-ADE Case: 70-year-old man with a history of hypertension. Right eye pain appeared on day X and was accompanied by blurred vision.
(h) Non-ADE Non-ADE Case: 79-year-old female. The patient had been taking prednisolone 60 mg and methotrexate 6 mg for 6 months following a diagnosis of middle vasculitis.

aADE: ADE suggesting.

bMTX: methotrexate.

cABPC/SBT: ampicillin/sulbactam.

dCEZ: cefazolin.

eRA: rheumatoid arthritis.

fNon-ADE: Non-ADE suggesting.

gTdP: torsades de pointes.