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. 2020 Dec 11;6:40. doi: 10.1038/s41531-020-00143-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Human orthologs of significantly differentially expressed Drosophila proteins that have been implicated in Parkinson’s disease through GWAS. Proteins are organized into 12 categories based on functional data provided by STRING. The degree of homology is indicted by the DIOPT score (blue, green, or orange filled circles). b Normalized levels of the Drosophila proteins in α-synuclein transgenic flies compared to controls. The solid black line indicates the control level of the protein. All the proteins plotted are significantly differentially expressed, p < 0.05, two-tailed t-test. All data are represented as mean ± SEM.