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. 2020 Dec 10;27:9–16. doi: 10.1016/j.jot.2020.10.011

Figure 3.

Figure 3

HGF-enhanced osteoclastogenesis and bone resorption was counteracted by SU11274. Representative TRAP staining images and analysis of osteoclasts cultured on day 3 derived from (a) RAW264.7 ​cells and (b) BMMs. RANKL (50 ​ng/mL); HGF (50 ​ng/mL); SU11274 (0.5 ​μM) (n ​= ​6). Scale bars, 100 ​μm. (c) Resorption pit assay of RAW264.7 ​cells and BMMs. Cells were incubated with or without HGF (50 ​ng/mL) in the absence or presence of SU11274 (0.5 ​μM) for 7d (n ​= ​6). Scale bars was 100 ​μm. At least 3 independent experiments were analyzed, and results are shown as means ​± ​SD; ∗p ​< ​0.05; n. s., not significant.