Fig. 3.

FGF10 coacervate mitigates inflammation, fibrosis and MI-associated injury. (A) Fibrosis in the infarct and border area was examined using Masson's trichrome staining 6 weeks after MI. Scale bars = 50 μm. Images of the first and second row showing collagen deposition in the border and infarct zones of different groups. (B–C) Quantitative results of infarct size and ventricular wall thickness in different treatment groups. (D) CD68 staining showing the distribution of macrophages in the infarct and border zone 2 weeks after MI injury. Scale bars = 50 μm. (E) Quantitative results of CD68⁺ cells in saline, free FGF10, heparin+FGF10 and FGF10 coacervate groups. * represents P < 0.05, ** represents P < 0.01, relative to saline group, free FGF10 or heparin+FGF10 group. All quantitative bars are represented as mean ± S.E.M.