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. 2020 Dec 11;10:168. doi: 10.1186/s13613-020-00786-1

Table 3.

Accuracy with which the collapsibility index of the inferior vena cava (cIVC) predicts fluid responsiveness

Breathing condition Site ROC [95% CI] Optimal threshold (%) Sensitivity Specificity
cIVC-ns 1 0.76 [0.66; 0.86]  > 35* 0.68 0.78
3 0.82 [0.74; 0.91]  > 20* 0.76 0.78
4 0.85 [0.78; 0.94]  > 33* 0.66 0.92
5 0.78 [0.68; 0.89]  > 19* 0.74 0.76
cIVC-st 1 0.73 [0.62; 0.84]  > 42* 0.76 0.66
3 0.80 [0.71; 0.91]  > 49* 0.76 0.85
4 0.98 [0.97; 1]  > 44* 0.93 0.98
5 0.83 [0.74; 0.92]  > 25* 0.87 0.67

Measurements of inferior vena cava (IVC) diameters were carried out at five sites: at the IVC-atrium, then at 1 (site 1), 3 (site 3), 4 (site 4) and 5 cm (site 5) caudal to the IVC-atrium junction. ROC area under the curve of receiver operating characteristics, CI confidence interval, cIVC-ns collapsibility index of the IVC in non-standardized breathing conditions, cIVC-st collapsibility index of IVC with standardized breathing manoeuvre. *Optimal threshold value to predict response to volume expansion