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MSC cells promoted invasion and tumor growth. (A) 3D cultures of naïve SCC-25, sorted SCC-25 and fused MSC/SCC cell in Matrigel/collagen allowing the cells to present a spheroidal morphology indicating invasion capacity was visualized by H&E. (B) Naïve SCC-25, sorted SCC-25, and fused MSC/SCC cell were injected in nude mice. Presented H&E and Ki67 IHC histological stains of the tumor observed in the tongue. MSC, Mesenchymal stem cells; SCC, squamous cell carcinoma.
