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. 2020 Dec 11;11(12):1050. doi: 10.1038/s41419-020-03239-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — (A) Circulating RIPK3 in critically ill patients with 1–4 of acute gastrointestinal injury (AGI) scores and healthy control (AGI score 0) was analyzed through enzyme-linked immunosorbent assay (ELISA). (B–D) Serum I-FABP, D-lactate, and IL-6 were assessed by ELISA. (E–G) Correlation between mtDNA and circulating was performed. mtDNA was analyzed via quantitative real-time PCR analysis by amplifying three kinds of mtDNA primers. *P < 0.05, **P < 0.01 vs control group.