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. 2020 Nov 4;23:132–141. doi: 10.1016/j.omtn.2020.10.041

Figure 5.

Figure 5

GCAT1 regulated GC proliferation and G1/S transition via p27

(A) The CCK8 assay showed the cell viability of KGN cells after GCAT1 silencing, CDKN1B silencing, and co-silencing. Results are expressed as the mean ± SD (n = 3). ∗∗∗p < 0.001 by two-tailed Student’s t test. (B and C) EdU staining assay showing the proliferation ability of KGN cells after GCAT1 silencing, CDKN1B silencing, and co-silencing. Results are expressed as the mean ± SD (n = 3). ∗∗∗p < 0.001 by two-tailed Student’s t test. (D) The flow cytometry cell cycle distribution of KGN cells after GCAT1 silencing, CDKN1B silencing, and co-silencing. Results are expressed as the mean ± SD (n = 3). ∗p < 0.05 by two-tailed Student’s t test.