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. 2020 Dec 10;10(12):e041921. doi: 10.1136/bmjopen-2020-041921

Table 4.

Sensitivity, specificity, AUC, PPV, NPV with 95% CI for each optional cut-off based on Youden’s criterion

No depression versus
≥mild depressive symptoms ≥moderate depressive symptoms ≥moderately severe depressive symptoms
Cut-off ≥3 ≥4 ≥4
Sensitivity (95% CI) 76.4 (73.8 to 78.8) 68.8 (63.3 to 73.9) 81.9 (71.1 to 90.0)
Specificity (95% CI) 62.2 (57.6 to 66.6) 54.7 (52.0 to 57.4) 51.7 (49.2 to 54.2)
PPV (95% CI) 83.6 (80.9 to 85.4) 26.0 (24.0 to 31.1) 7.2 (6.5 to 13.3)
NPV (95% CI) 51.0 (47.6 to 55.8) 88.3 (85.6 to 89.4) 98.4 (97.2 to 98.6)
J 0.39 0.24 0.34
AUC (95% CI) 0.73 (0.70 to 0.75) 0.66 (0.62 to 0.69) 0.73 (0.67 to 0.79)
SE 0.01 0.02 0.03
z 17.17*** 9.01*** 7.45**

***p<0.000; **p<0.01.

AUC, area under the curve; J, Youden’s index; NPV, negative predictive value; PPV, positive predictive value.;