Antiviral activity of HepDirect prodrugs of pyrimidines
aConcentration of nucleoside triphosphate (NTP) at 2 h after incubation at 25 μM. bConcentration of NTP at 3 h after 5 mg/kg intraperitoneal injection. cConcentration of NTP at 3 h after an oral dose of 10 mg/kg. dParent nucleoside. e4 mg/kg. f8 mg/kg. BLD, below limit of detection; C, cytosine; Me, methyl; Pr, propyl; U, uracil.