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. 2020 Dec 11;17:65. doi: 10.1186/s12970-020-00396-z

Table 4.

Blood biochemestry results

TRE ND 2 Way ANOVA
Time*Diet
Main time effect Main diet effect
Pre Post Pre Post
Complete blood count
 RBC (106/μL) 4.95 ± 0.38 4.90 ± 0.28 5.11 ± 0.40 5.09 ± 0.44 ns ns ns
 HGB (g/L) 152.63 ± 11.50 148.13 ± 7.90 153.50 ± 10.53 151.38 ± 11.70 ns ns ns
 HCT (%) 46.90 ± 2.80 44.41 ± 2.17* 47.01 ± 2.99 45.45 ± 3.24 ns 0.0035 ns
 MCV (fL) 93.23 ± 1.98 90.60 ± 2.72* 92.08 ± 3.75 89.46 ± 4.17* ns 0.0001 ns
 MCH (pg) 30.85 ± 0.89 30.23 ± 1.05 30.06 ± 1.27 29.74 ± 0.98 ns 0.0069 ns
 MCHC (g/L) 331.15 ± 9.66 334.04 ± 7.59 326.55 ± 6.84 332.89 ± 8.66 ns ns ns
 RDW (%) 12.79 ± 0.66 12.91 ± 0.62 12.83 ± 0.31 12.65 ± 0.65 ns ns ns
 Platelet (103/μL) 231.38 ± 35.90 220.25 ± 45.86 244.25 ± 35.29 232.75 ± 43.75 ns ns ns
White blood cells
 Eosinophils (%) 3.06 ± 3.34 3.19 ± 3.06 3.63 ± 6.16 2.56 ± 2.09 ns ns ns
 Basophiles (%) 0.75 ± 0.29 0.74 ± 0.24 0.44 ± 0.24 0.65 ± 0.40 ns ns ns
 Monocytes (%) 6.83 ± 2.11 6.10 ± 1.47 6.25 ± 0.87 7.40 ± 1.21 0.0241 ns ns
Chemistry
 Glucose (mg/dL) 94.63 ± 5.45 90.25 ± 6.54 91.00 ± 5.15 91.25 ± 6.94 ns ns ns
 Creatinine (mg/dL) 0.86 ± 0.11 0.84 ± 0.10 0.85 ± 0.10 0.81 ± 0.10* ns 0.0072 ns
 Creatine kinase (mg/dL) 309.13 ± 227.94 273.38 ± 202.78 289.63 ± 388.26 231.50 ± 114.35 ns ns ns
 Total cholesterol (mg/dL) 171.00 ± 18.52 181.38 ± 41.59 176.25 ± 17.56 179.38 ± 31.08 ns ns ns
 TG (mg/dL) 69.75 ± 26.13 54.13 ± 20.23 70.50 ± 54.51 70.38 ± 56.89 ns ns ns
 Iron (μg/dL) 110.13 ± 63.41 143.25 ± 30.16 97.63 ± 23.30 108.38 ± 37.39 ns ns ns
 Ferritin (μg/L) 101.25 ± 28.34 101.75 ± 35.23 143.38 ± 57.67 110.63 ± 62.62 ns ns ns
 Transferrin (mg/dL) 253.38 ± 23.20 243.13 ± 19.62 270.63 ± 29.42 257.63 ± 29.26 ns ns ns
 CRP (mg/dL) 0.18 ± 0.17 0.08 ± 0.06 0.08 ± 0.06 0.07 ± 0.04 ns ns ns
 ESR (mm/h) 2.75 ± 1.75 4.13 ± 2.10 2.00 ± 0.00 3.00 ± 1.07 ns 0.0138 ns
Hormones
 TSH (mcIU/mL) 2.23 ± 0.99 2.11 ± 1.34 1.79 ± 0.63 1.63 ± 0.46 ns ns ns
 T3 free (pg/mL) 3.33 ± 0.42 3.13 ± 0.47 3.12 ± 0.40 3.39 ± 0.40 0.0114 ns ns
 Testosterone free (pg/mL) 33.73 ± 7.56 24.33 ± 7.23* 41.51 ± 14.09 38.33 ± 12.60# ns 0.0045 0.0497
 SHBG (nmol/L) 36.09 ± 13.85 32.73 ± 12.85 35.79 ± 10.69 31.98 ± 9.32 ns 0.0356 ns
 Cortisol (ug/dL) 16.63 ± 2.79 11.78 ± 1.85* 15.48 ± 4.36 12.04 ± 4.74* ns 0.0005 ns
 Insulin (uIU/mL) 5.25 ± 1.75 3.88 ± 1.96 5.63 ± 1.60 5.50 ± 2.88 ns ns ns
 IL-6 (pg/mL) 2.59 ± 1.13 2.24 ± 0.42 2.15 ± 0.42 2.73 ± 0.71 ns ns ns
 Adiponectin (μg/mL) 3.00 ± 1.46 4.00 ± 2.24 4.63 ± 1.94 4.95 ± 2.30 ns ns ns
 Adiponectin/FM (μg/mL/kg) 0.28 ± 0.14 0.39 ± 0.16* 0.43 ± 0.22 0.43 ± 0.22 ns 0.0488 ns
 TNF (pg/mL) 7.26 ± 2.35 7.45 ± 2.99 7.24 ± 1.75 7.39 ± 2.84 ns ns ns
 IGF-1 (ng/mL) 244.03 ± 90.83 291.60 ± 58.29* 329.60 ± 92.71 330.94 ± 62.71 ns ns ns

Results are presented as mean ± SD

TRE time restricted eating, ND normal diet

* Significantly different from pre values (p < 0.05); # significantly different from TRE group (p < 0.05)