Table 1.
Demographics and Baseline and Outcome Characteristics Stratified by SIRS
| All Patients (n=256) |
Non-SIRS (n=165) |
SIRS (n=91) |
P-value | Odds Ratio (95% CI) |
P-value | |
|---|---|---|---|---|---|---|
| Age, mean (SD), y | 68.1 (11.6) | 67.9 (11.7) | 68.4 (11.7) | 0.787 | ||
| Male, n (%) | 139 (54.3) | 86 (52.1) | 53 (58.2) | 0.347 | ||
| Hypertension | 180 (70.3) | 106 (64.2) | 74 (81.3) | 0.004 | ||
| Diabetes mellitus | 43 (16.8) | 23 (13.9) | 20 (22.0) | 0.100 | ||
| Clinical characteristics, median (IQR) | ||||||
| Baseline NIHSS score | 16 (13–19) | 14 (12–18) | 18 (15–20) | <0.001 | 1.115 (1.022–1.217) | 0.014 |
| Baseline ASPECT score | 8 (8–10) | 9 (8–10) | 8 (8–9) | 0.006 | ||
| Stroke cause, n (%) | ||||||
| LAA | 84 (32.8) | 59 (35.8) | 25 (27.5) | 0.195 | ||
| Cardioembolic | 141 (55.1) | 84 (50.9) | 57 (62.6) | |||
| Undetermined or other | 31 (12.1) | 22 (13.3) | 9 (9.9) | |||
| Occlusion site, n (%) | ||||||
| ICA | 107 (41.8) | 62 (37.6) | 45 (49.5) | 0.065 | ||
| MCA | 149 (58.2) | 103 (62.4) | 46 (50.5) | |||
| OTP, median (IQR) | 260 (210–300) | 270 (212–300) | 255 (210–300) | 0.411 | ||
| Bridging therapy, n (%) | 32 (12.5) | 23 (13.9) | 9 (9.9) | 0.348 | ||
| Collateral score, n (%) | ||||||
| Grade 0 | 58 (22.7) | 21 (12.7) | 37 (40.7) | <0.001 | Reference | |
| Grade 1 | 99 (38.7) | 63 (38.2) | 36 (39.6) | 0.346 (0.153–0.783) | 0.011 | |
| Grade 2 | 99 (38.7) | 81 (49.1) | 18 (19.8) | 0.225 (0.093–0.545) | 0.001 | |
| mTICI, 2b/3, n (%) | 187 (73.0) | 125 (75.8) | 62 (68.1) | 0.188 | ||
| Independence at 90 days, n (%) | 113 (44.1) | 100 (60.6) | 13 (14.3) | <0.001 | ||
| Mortality at 90 days, n (%) | 64 (25.0) | 10 (6.1) | 54 (59.3) | <0.001 | ||
| Laboratory examination | ||||||
| FBG*(mmol/L), mean (SD) | 7.4 (3.5) | 6.5 (2.6) | 8.9 (4.4) | <0.001 | 1.140 (1.036–1.256) | 0.007 |
| Leucocytes, 109/L | 10.2 (8.3–13.3) | 9.4 (7.9–11.3) | 13.7 (10.8–17.2) | <0.001 | ||
| Neutrophils,109/L | 8.7 (6.8–11.6) | 7.7 (6.5–9.5) | 12.0 (9.4–15.2) | <0.001 | 1.367 (1.219–1.534) | <0.001 |
| Lymphocytes, 109/L | 0.9 (0.7–1.3) | 1.0 (0.7–1.4) | 0.8 (0.6–1.2) | 0.011 |
Note: *Missing data in six patients.
Abbreviations: SIRS, systemic inflammatory response syndrome; ASPECT, Alberta Stroke Program Early CT; ICA, internal carotid artery; LAA, large-artery atherosclerosis; mTICI, modified thrombolysis in cerebral infarction; ICA, internal carotid artery; MCA, middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale; OTP, symptom onset to groin puncture time; FBG, fasting blood glucose.