Table 2.
Comparison of the Variables Stratified by Outcome in the Overall Cohort
| Favorable Outcome (n=113) |
Poor Outcome (n=143) |
P-value | Odds Ratio (95% CI) |
P-value | |
|---|---|---|---|---|---|
| Age, mean (SD), y | 65.7 (11.2) | 69.9 (11.8) | 0.004 | ||
| Male, n (%) | 70 (61.9) | 69 (48.3) | 0.029 | 2.043 (0.984–4.242) | 0.055 |
| Medical history, n (%) | |||||
| Hypertension | 75 (66.4) | 105 (73.4) | 0.220 | ||
| Diabetes mellitus | 12 (10.6) | 31 (21.7) | 0.019 | ||
| Clinical characteristics, median (IQR) | |||||
| Baseline NIHSS score | 14 (12–18) | 17 (14–20) | <0.001 | ||
| Baseline ASPECT score | 9 (8–10) | 8 (8–9) | <0.001 | 0.680 (0.491–0.942) | 0.020 |
| Stroke cause, n (%) | |||||
| LAA | 50 (44.2) | 34 (23.8) | <0.001 | ||
| Cardioembolic | 47 (41.6) | 94 (65.7) | |||
| Undetermined or other | 16 (14.2) | 15 (10.5) | |||
| Occlusion site, n (%) | |||||
| ICA | 33 (29.2) | 74 (51.7) | <0.001 | 2.663 (1.287–5.514) | 0.008 |
| MCA | 80 (70.8) | 69 (48.3) | Reference | ||
| OTP, median (IQR) | 270 (224–303) | 250 (210–300) | 0.208 | ||
| Bridging therapy, n (%) | 16 (14.2) | 16 (11.2) | 0.475 | ||
| Collateral score, n (%) | |||||
| Grade 0 | 8 (7.1) | 50 (35.0) | <0.001 | Reference | |
| Grade 1 | 38 (33.6) | 61 (42.7) | 0.344 (0.119–0.994) | 0.049 | |
| Grade 2 | 57 (59.3) | 32 (22.4) | 0.115 (0.038–0.343) | <0.001 | |
| mTICI, 2b/3, n (%) | 98 (86.7) | 89 (62.2) | <0.001 | 0.223 (0.095–0.525) | 0.001 |
| SIRS, n (%) | 13 (11.5) | 78 (54.5) | <0.001 | 4.112 (1.705–9.920) | 0.002 |
| Laboratory examination | |||||
| FBG* (mmol/L), mean (SD) | 6.1 (2.2) | 8.4 (4.0) | <0.001 | ||
| Leucocytes, 109/L | 9.3 (7.9–11.3) | 11.8 (8.9–14.8) | <0.001 | ||
| Neutrophils,109/L | 7.7 (6.4–9.5) | 10.1 (7.4–12.7) | <0.001 | 1.171 (1.032–1.328) | 0.015 |
| Lymphocytes, 109/L | 1.1 (0.7–1.4) | 0.8 (0.6–1.2) | 0.005 |
Note: *Missing data in six patients.
Abbreviations: SIRS, systemic inflammatory response syndrome; ASPECT, Alberta Stroke Program Early CT; ICA, internal carotid artery; LAA, large-artery atherosclerosis; mTICI, modified thrombolysis in cerebral infarction; ICA, internal carotid artery; MCA, middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale; OTP, symptom onset to groin puncture time; FBG, fasting blood glucose.