Table 2.
Kinetic Model | Fitting Equation | Regression Equation | R2 |
---|---|---|---|
Zero order | Mt/M∞=Kt | y=0.02325x | 0.40513 |
First order | Mt/M∞=1-e−Kt | y=1-e−0.7732x | 0.68571 |
Higuchi | Mt/M∞= Kt0.5 | y=0.54861 x0.5 | 0.92137 |
Korsmeyer-Peppas | Mt/M∞= Ktn | y=0.20135 x0.43718 | 0.94183 |
Notes: Mt/M∞ is the cumulative drug release percentage at a given moment, t is the release time and K is the release constant.