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. 2020 Dec 8;7:361–376. doi: 10.2147/JHC.S279123

Table 1.

Correlation of LRP1B and HSF1 Expression and Clinicopathologic Parameters in HCC Patients

Variable HSF1 LRP1B
Low High P Low High P
sex 0.751 0.453
Male 170 55 93 132
Female 25 7 11 21
age 0.233 0.038*
≤50 90 34 42 82
>50 105 28 62 71
HBsAg 0.703 0.418
negative 25 9 16 18
positive 167 52 87 132
serum AFP 0.004* 0.008*
≤20ng/mL 77 12 46 43
>20ng/mL 116 49 57 108
Liver cirrhosis 0.117 0.141
no 68 15 39 44
yes 127 47 65 109
TNM 0.32 0.355
I 73 14 37 50
II 92 41 56 77
III–IV 30 7 11 26
Child-Pugh class 0.496 0.682
A 177 58 96 139
B 18 4 8 14
Tumor size 0.284 0.282
≤5cm 97 26 54 69
5cm 98 36 50 84
Tumor number 0.594 0.413
single 151 50 84 117
multiple 44 12 20 36
tumor differentiation 0.072 0.520
well 22 3 12 13
moderate 173 58 92 139
poor 0 1 0 1
vascular invasion 0.033* 0.889
no 83 17 41 59
yes 112 45 63 94

Note: *P<0.05 shown in bold means statistical significance.

Abbreviations: HBsAg, hepatitis B surface antigen; AFP, alpha-fetoprotein; TNM, tumor-node-metastasis.