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. 2020 Dec 12;11(12):1055. doi: 10.1038/s41419-020-03257-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Representative images of pulmonary metastatic models. b Statistical analysis of colony numbers of pulmonary metastases between SCC9-AC007271.3 and SCC9-NC group (n = 5). c The expression of AC007271.3 and miR-125b-2-3p in pulmonary metastases were detected by qRT-PCR. d Representative images of HE and IHC staining. Higher level of Slug was detected in SCC9-AC007271.3 group than that in SCC9-NC group. e Western blot confirmed the upregulation of Slug and the downregulation of E-cadherin in SCC9-AC007271.3 group. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.