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. 2020 Dec 11;5:55. doi: 10.1038/s41525-020-00159-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Box plots for the mean PSI value difference for top NMF events between the two IR-based clusters of different cancer types. The number in parenthesis indicates the number of patients for that cancer type. b Heatmaps comparing the IR levels of top NMF events between the two clusters of KIRC and PRAD cancer types. z-scores (calculated using the PSI values) are represented by red and blue colors indicating high and low IR levels, respectively. c OS and PFI plots comparing the two clusters of KIRC and PRAD, respectively. p values were determined by log-rank (Mantel−Cox) test; n number of patients (tumors). d Venn diagram showing the overlap between the three groups of RBP genes that significantly change in expression between the two clusters of PDAC, PRAD, and KIRC, respectively.