Fig. 6. Phylogenetic tree depicting the overall distribution of core donor ASVs classified as Firmicutes among the two HMA animal models.

Red squares indicate the presence of core Firmicutes ASVs in the human donors while the green squares and blue squares indicate which of those Firmicutes ASVs were able to colonize the HMA mice and piglets, respectively. Green stars indicate persistent colonizers of HMA mice and blue stars indicate persistent colonizers of HMA piglets. n = 13 (3 piglets/donor, with the exception n = 4 for Donor_1, 2 days post inoculation) and n = 37 mice (Donor_1 = 7, Donor_2 = 10, Donor_3 = 10, Donor_4 = 10).