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. 2020 Oct 6;36(6):962–966. doi: 10.1002/joa3.12439

TABLE 1.

SQTS classification is based on genotype

SQTS subtype Gene Channel function Mechanism
SQTS 1 KCNH2 α‐subunit IKr Gain function
SQTS 2 KCNQ1 α‐subunit IKs Gain function
SQTS 3 KCNJ1 α‐subunit IK1 Gain function
SQTS 4 CACNA1C α‐subunit IL,Ca Loss function
SQTS 5 CACNB2 Β2‐subunit IL,Ca Loss function
SQTS 6 CACNA2D1 Δ1‐subunit IL,Ca Loss function