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. 2020 Dec 12;11(12):1057. doi: 10.1038/s41419-020-03267-2

Fig. 7. HDAC inhibitors protect from AKI by regulating the expression of PSTPIP2.

Fig. 7

a Immunohistochemical localisation of PSTPIP2 expression in the kidney tissues. Scale bar, 50 μM; magnification, 20×. b The expression of cleaved caspase-3, H3K27Ac, KIM-1 and PSTPIP2 detected by western blot in CP-treated AKI mice administered with TSA. c The expression of cleaved caspase-3, H3K27Ac, KIM-1 and PSTPIP2 detected by western blot in CP-treated HK-2 cells treated with TSA. Similar results were obtained in 3 independent experiments with 10 mice per group or in triplicate culture assays.