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. 2020 Dec 8;11(49):4554–4569. doi: 10.18632/oncotarget.27832

Figure 6. Differential tumor-associated macrophage phenotype in female and OVX mice.

Figure 6

(A) Representative gating strategy for sorting of tumor associated macrophages, defined as CD45+ F4/80+ CD11b+ cells. (B) Percentage of tumor associated macrophages within tumors at the time of sort. (C and D) Relative gene expression of CD11c (C) and CD206 (D) in collected tumor associated macrophages. Ct values relative to average of multiple internal controls determined using qBASE pro software analysis. Ct values normalized to LFD Female group. Values are means ± SE; n = 3–4 mice per group. Bar graphs not sharing a common letter are significantly different from one another (p ≤ 0.05).