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. 2020 Dec 14;21(Suppl 17):484. doi: 10.1186/s12859-020-03782-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Predicted SARS-CoV-2-specific CD8⁺ T cell epitopes using iPCPS. a The figure represents the number of predicted CD8⁺ T cell epitopes in SARS-CoV-2 proteome using iPCPS with different settings indicated in the abscissa: 9-mer, total 9-mer peptides in the SARS-CoV-2 proteome; IP, immunoproteasome model; IP w/o, immunoproteasome model discarding peptides with internal cleavage sites; IP + P, immunoproteasome and proteasome models; IP + P w/o, immunoproteasome and proteasome models discarding peptides with internal cleavage sites. b Percentage of SARS-CoV-2 CD8⁺ T cell epitopes predicted by peptide-HLA I binding predictions reported by Grifoni et al. [31] included in those anticipated by iPCPS with settings indicated in panel A