Fig. 2.

Biodistribution of [¹¹¹In]In-DTPA-28H1 and [¹¹¹In]In-DTPA-28H1-IRDye700DX with SR 2.3 or 6.5

(A) Biodistribution of the DTPA-28H1-700DX conjugate is different compared with DTPA-28H1, with most strikingly with a higher liver accumulation. (B) Tracer accumulation in the knee joint is not negatively affected by conjugation to the PS. (C) Tracer uptake in the bone marrow seems to increase, but this was not statistically significant. Data are shown as mean (s.d.). Two-way analysis of variance with Bonferroni post-test. *P < 0.05, ***P < 0.001; n = 5 mice/group.