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. Author manuscript; available in PMC: 2021 Feb 21.
Published in final edited form as: Sci Immunol. 2020 Aug 21;5(50):eabb4432. doi: 10.1126/sciimmunol.abb4432

Fig. 7. Cells from a CD8+ TRM cell cluster with enhanced inflammatory properties are increased in affected colonic tissue from UC patients.

Fig. 7.

(A) Violin plots of selected genes differentially expressed by the four CD8+ TRM cell clusters (T1, T2, T10, T14). (B) Pathway analysis of genes differentially expressed by the T10 CD8+ TRM cluster compared to all other CD8+ TRM clusters. (C) Representative H&E-stained images of unaffected vs. affected colonic tissue from a UC patient used for RNA in situ hybridization (ISH) analyses shown in D, E. Representative ISH images of affected colonic tissue (D) and quantitation of CD8+CD69+EOMES+ cells from unaffected vs. affected regions of colonic tissue from UC patients (n=5) (E). Paired Student’s t-test (E). ** p < 0.01.