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. 2020 Nov 30;14:571480. doi: 10.3389/fnins.2020.571480

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Copyright © 2020 Shao, Jann, Ma, Yan, Montagne, Ringman, Zlokovic and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Scatter plot of whole-brain (A) and regional (B–I) Ktrans vs. kw from test and retest scans. β is the regression coefficient of the mixed-effect linear regression. Significant correlation was found in white matter (β = 6.7 × 10⁴, P = 0.036), caudate (β = 8.6 × 10⁴, P = 0.029), and MCA perforator territory (β = 6.9 × 10⁴, P = 0.009).