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Ktrans and kGad (A) and test-retest kw (B) maps from subjects with (top row) and without (bottom row) WMH. (C) FLAIR, Ktrans, kGad, and kw maps (first visit) in normalized MNI space from the same subject as shown in the top row. Ktrans, kGad, and kw maps were overlaid on the FLAIR image. One WMH lesion was indicated by a red arrow and a dashed red circle and WMH penumbra was indicated by an orange circle on each image.
