Table 1.
Demographic characteristics of 16 subjects recruited in this study.
| Count | Column N% | ||
|---|---|---|---|
| Sex | Male | 3 | 18.8% |
| Female | 13 | 81.3% | |
| Age range (years) | 62–86 | ||
| Vascular risk factor | Diabetes | 7 (of 15) | 46.7% |
| Hypertension | 8 (of 15) | 53.3% | |
| Hypercholesterolemia | 12 (of 15) | 80.0% | |
| Global CDR scale | 0 (Normal) | 12 | 75.0% |
| 0.5 (Very mild dementia) | 4 | 25.0% | |
| Fazekas scale | ≤1 (Mild WMH) | 4 | 25.0% |
| 2 (Moderate WMH) | 9 | 56.3% | |
| 4 (Severe WMH) | 3 | 18.8% | |
Vascular risk factors (presence of diabetes, hypertension or hypercholesterolemia) was defined by a past diagnosis and/or current treatment for these conditions from 15 subjects (clinical record of one subject was missing). Neurocognitive performance was evaluated by global Clinical Dementia Rating (CDR) scale. Severity of white matter lesions were quantified by the total Fazekas scale, which is the sum of 2 scales rated from 0 (absent) to 3 (large confluent areas) in periventricular white matter and deep white matter.