TABLE 1.
Clinicopathological characteristics of lung adenocarcinoma patients
| Characteristics | Total | CD109‐low | CD109‐high | χ 2 test | ||
|---|---|---|---|---|---|---|
| (%) | (%) | P value | ||||
| Number | 200 | 124 | (62.0) | 76 | (38.0) | |
| Age (y) | ||||||
| <65 | 70 | 44 | (22.0) | 26 | (13.0) | 0.855 |
| ≥65 | 130 | 80 | (40.0) | 50 | (25.0) | |
| Sex | ||||||
| Male | 106 | 48 | (24.0) | 58 | (29.0) | <0.0001 |
| Female | 94 | 76 | (38.0) | 18 | (9.0) | |
| Smoking history | ||||||
| Never | 90 | 70 | (46.4) | 20 | (13.2) | 0.0113 |
| Smoked | 61 | 35 | (23.2) | 26 | (17.2) | |
| Unknown | 49 | 19 | 30 | |||
| Pleural invasion | ||||||
| (–) | 152 | 113 | (56.5) | 39 | (19.5) | <0.0001 |
| (+) | 48 | 11 | (5.5) | 37 | (18.5) | |
| Lymphovascular infiltration | ||||||
| (–) | 163 | 117 | (58.5) | 46 | (23.0) | <0.0001 |
| (+) | 37 | 7 | (3.5) | 30 | (15.0) | |
| T classification | ||||||
| Tis | 25 | 25 | (12.5) | 0 | (0.0) | <0.0001 |
| T1 | 103 | 79 | (39.5) | 24 | (12.0) | |
| T2 | 57 | 17 | (8.5) | 40 | (20.0) | |
| T3 and 4 | 15 | 3 | (1.5) | 12 | (6.0) | |
| N classification | ||||||
| N0 | 175 | 119 | (59.5) | 56 | (28.0) | <0.0001 |
| N1, 2, and 3 | 25 | 5 | (2.5) | 20 | (10.0) | |
| Clinical stage | ||||||
| 0 | 25 | 25 | (12.5) | 0 | (0.0) | <0.0001 |
| I | 134 | 89 | (44.5) | 45 | (22.5) | |
| II | 23 | 4 | (2.0) | 19 | (9.5) | |
| III | 18 | 6 | (3.0) | 12 | (6.0) | |
| EGFR mutation | ||||||
| Nondetected | 91 | 41 | (24.1) | 50 | (29.4) | <0.0001 |
| Detected | 79 | 64 | (37.6) | 15 | (8.8) | |
| Unknown | 30 | 19 | 11 | |||