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NTCD-035 lacks pathogenicity in germ free mice
(a-c) Germfree C57BL/6 mice were mono-colonized with either the VPI10463 or NTCD-035 spores by oral gavage. (a) Percent of initial weight of infected groups from day of infection. (B) Survival of mice infected with different strains. (c) C. difficile burden in fecal pellets collected from infected mice. n = 5 mice/group. LOD – Limit of Detection. * = p < .05, ** = p < .01.”
