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. 2020 Dec 14;11(12):1065. doi: 10.1038/s41419-020-03276-1

Fig. 7. Knockout of hsa_circ_104348 inhibited HCC progression in mice treated with Huh7 cell transfected with sh-circRNA or sh-NC plasmid.

Fig. 7

A The expression of hsa_circ_104348 and miR-187-3p was detected by qRT-PCR. B The effect of hsa_circ_104348 silencing on tumor volume curve and tumor weight were analyzed. C The scale bars were 50 μm. The expression of RTKN2, β-catenin, Ki67, E-cadherin, N-cadherin was determined by IHC. D Lung metastasis was detected by in vivo images. E Metastatic focis from mice were shown. F HE-staining of pulmonary nodules from mice. The scale bars were 500 μm. Data were expressed as mean ± SD.