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. 2020 Nov 30;11:592543. doi: 10.3389/fphar.2020.592543

FIGURE 5.

FIGURE 5

Medical history of patients one and two from admission time to hospital discharge. This table shows clinical course of major symptoms and signs, blood biochemistry and viral shedding on initial therapy (azithromycin and/or hydroxychloroquine) as well as changes of these parameters upon start of IFN-β-1b therapy until hospital discharge. Respiratory scores: 0, No oxygen; 1, oxygen through nasal cannula or mask; 2, mask with high O2 concentration; 3, optiflow and/or NIV (Non-Invasive Ventilation); 4, mechanical ventilation with PEP ≤ 6 cm H2O or FiO2 ≤ 0.6; and 5, mechanical ventilation with PEP > 6 cm H2O and FiO2 > 0.6. p, prone therapy (18 h). ARDS scores: 0, no ARDS; 1, light ARDS; 2, moderate ARDS; 3, severe ARDS (corresponding to Berlin ARDS definition). CRP, C-reactive protein; ARDS, acute respiratory distress syndrom; T°C, temperature; G, giga.