Table 1.
Organ | Lesion | Animal no |
||
---|---|---|---|---|
1 | 2 | 3 | ||
Nasal turbinate | Exfoliation of the epithelial cells (Fig. 2A) | +++ | + | ++ |
Propria-submucosal lesions (Figs. 2B and C) | +++ | + | ++ | |
Focal areas of epithelial hyperplasia | + | + | + | |
Trachea | Partial loss of cilia, epithelial vacuolation and intra-epithelial infiltration with neutrophils (Fig 2D) | – | – | ++ |
Bronchi | Hyperplasia of bronchial epithelia | – | + | + |
Lungs | Interstitial pneumonia (Figs. 2E and Fig 3) | ++ | +++ | +++ |
Bronchopneumonia with many segmented neutrophils in bronchioli and alveoli | – | +++ | – | |
Spleen | chronic hyperplasia with widened red pulp and depleted white pulp | – | – | + |
Kidney | Glomerular and tubular lesions (Fig 2F). | ++ | + | ++ |