Table 4.
Serum levels of inflammatory cytokines on SLE patients and healthy controls.
| Molecules | Controls (N = 32) | SLE patients (N = 82) | P-value |
|---|---|---|---|
| IL-6 | 1.77 (3.24) | 2.77 (1.44) | <0.001 |
| IL-10 | 0.22 (1.12) | 1.41 (0.47) | <0.001 |
| IFNα | 2.86 (1.30) | 8.53 (8.72) | <0.001 |
| IL-17A | 3.49 (10.11) | 4.50 (12.59) | 0.822 |
| TNFα | 42.64 (116.17) | 164.98 (125.50) | <0.001 |
| IFNγ | 3.14 (3.10) | 2.72 (2.51) | 0.149 |
| BLyS | 490.11 (154.40) | 1887.56 (782.77) | <0.001 |
| ICAM-1 | 255.56 (215.43) | 286.03 (160.99) | 0.284 |
| CXCL10 (IP-10) | 48.30 (36.24) | 58.33 (57.33) | <0.001 |
| CCL2 (MCP-1) | 204.97 (164.63) | 167.48 (109.15) | 0.388 |
| CCL3 (MIP1α) | 0.20 (0.00) | 6.44 (51.12) | <0.001 |
| CCL5 (RANTES) | 20.78 (12.66) | 16.01 (12.21) | 0.083 |
Values represent median (interquartile range) (pg/ml).
Differences analyzed by U-Mann-Whitney test. Bold values represent statistically signifcant ones (p < 0.05).