Table 3.
Maintaining Cost of Vancomycina and Initial Rate of Infectionb Constant Changes Cost-Effectiveness.
| Cost of Treating Infection (US$) | Laminectomy | Laminectomy and Fusion | ||
|---|---|---|---|---|
| Final Infection Rate (%) | ARR (%) | Final Infection Rate (%) | ARR (%) | |
| 500 | 3.59 | 0.6120 | 7.89 | 0.6120 |
| 1000 | 3.89 | 0.3060 | 8.19 | 0.3060 |
| 5000 | 4.14 | 0.0612 | 8.44 | 0.0612 |
| 10 000 | 4.17 | 0.0306 | 8.47 | 0.0306 |
| 21 060c | 4.19 | 0.0145 | 8.49 | 0.0145 |
| 30 000 | 4.19 | 0.0102 | 8.49 | 0.0102 |
| 40 000 | 4.19 | 0.0077 | 8.49 | 0.0076 |
| 50 000 | 4.19 | 0.0061 | 8.49 | 0.0061 |
| 75 000 | 4.20 | 0.0041 | 8.50 | 0.0041 |
| 90 938d | 4.20 | 0.0034 | 8.50 | 0.0034 |
| 100 000 | 4.20 | 0.0031 | 8.50 | 0.0031 |
| 120 000 | 4.20 | 0.0025 | 8.50 | 0.0025 |
Abbreviation: ARR, absolute risk reduction.
a Cost of vancomycin $3.06 per gram at our institution.
b Presumes initial rate of infection is 4.20% for laminectomy and 8.50% for laminectomy and fusion.
c Denotes literature value of treating infected laminectomy.
d Denotes literature value of treating infected laminectomy and fusion.