Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 30;11:593103. doi: 10.3389/fimmu.2020.593103

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Iwata, Zhang, Hao, Trimova, Hajime, Miyazaki, Ohkubo, Satoh Kanda, Todoroki, Miyata, Ueno, Nagayasu, Nakayamada, Sakata and Tanaka

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The relation of percentage of CXCR3^loT-bet^hiCD4⁺ cells to clinical background in patients with SLE. Pearson correlation coefficient was used to test the relation between the percentage of CD4⁺CXCR3^loT-bet^hi cells and each factor. Treatment resistance was defined as lack of clinical response to ≥3 kinds of immunosuppressants and/or ≥2 re-increase in high-dose corticosteroid. SLEDAI; SLE disease activity score, BILAG; British Isles Lupus Assessment Group, ANA; Anti-nuclear antibody, Anti-Sm Abs; anti-Smith antibody, Anti-double stranded DNA antibody. The relation of the percentage of CXCR3^loT-bet^hi CD4⁺ cells to the factors of corticosteroid use and treatment resistance were analyzed using unpaired t-test. A p-value of <0.05 denoted the presence of statistical significance. Statistical analyses were conducted using the Prism software (Prism Software, Irvine, CA). **p < 0.01.