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. 2020 Nov 30;8:612950. doi: 10.3389/fbioe.2020.612950

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Copyright © 2020 Li, Luo, Li, Xia, Wang and Fu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of various kinds of surface modified MSR scaffolds in therapeutic effect. (A) The experimental procedure of treatment. (B) Mice after injected with different modified MSR scaffolds, including unmodified MSRs (OH), PEG modified MSRs (PEG) and Poly (ethylene glycol) and integrin-binding ligand Arg-Gly-Asp modified MSRs (PEG-RGD). (C) Weight of the fibrous capsules. (D) Percentage of CD11c+ and CD11b+ cells in the scaffolds. (Reproduced with permission from Li W.A. et al. (2016). Unmodified MSRs, PEG MSRs, PEG-RGD MSRs and PEG-RDG MSRs were injected subcutaneously into the flank of mice. Poly (ethylene glycol) (PEG) and integrin-binding ligand Arg-Gly-Asp (RGD).