TABLE 1.
No. of platelets | Granules/per platelet | Mitochondria/per platelet | ||
---|---|---|---|---|
No | p | No | p | |
Resting platelets (11) | 9.8 ± 0.85 | — | 3.5 ± 0.22 | — |
Thrombin (13) | 4.6 ± 0.46 | < 0.01 | 1.3 ± 0.28 | < 0.05 |
Thrombin + Linagliptin (8) | 10.6 ± 1.04 | < 0.05 | 3.4 ± 0.37 | < 0.05 |
Linagliptin (9) | 9.6 ± 0.78 | < 0.05 | 2.8 ± 0.37 | < 0.05 |
Values are presented with SEM. p values were determined by using the two-way analysis of variance to compare each number of granules and mitochondria to resting and thrombin-activated platelets.